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CYCLIN-DEPENDENT KINASE 2
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DeCS
Descriptor
English
:
Cyclin-Dependent Kinase 2
Descriptor
Spanish
:
cinasa 2 dependiente de la ciclina
Descriptor
Portuguese
:
Quinase 2 Dependente de Ciclina
Synonyms
English
:
CDK2 Protein
Cdc2 Related Protein Kinase
Cdc2-Related Protein Kinase
Cdk2 Protein Kinase
Cyclin Dependent Kinase 2
p33cdk2 Kinase
Tree Number:
D08.811.913.696.620.682.700.646.500.750
D12.644.360.250.323
D12.776.167.200.323
D12.776.476.250.323
Definition
English
:
A key regulator of
CELL CYCLE
progression. It partners with
CYCLIN E
to regulate entry into
S PHASE
and also interacts with
CYCLIN A
to phosphorylate
RETINOBLASTOMA PROTEIN
. Its activity is inhibited by
CYCLIN-DEPENDENT KINASE INHIBITOR P27
and
CYCLIN-DEPENDENT KINASE INHIBITOR P21.
History Note
English
:
2006(1991)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
50714
Unique Identifier:
D051357
Occurrence in VHL
:
Similar:
DeCS